Paramyxovirus associated with pneumonia in a Dwarf rabbit

 R. Ducatelle, D. Vanrompay, G. Charlier


Respiratory diseases in rabbits usually are associated with Pasteurella multocida infections. With the exception of myxomatosis and Rabbit Haemorrhagic disease, naturally occurring viral respiratory diseases have not been described in rabbits to our knowledge. In this report a natural outbreak of acute fatal pneumonia associated with the presence of paramyxovirus-like particles is described. The lung lesion was characterized by giant cell alveolitis. The results of this study should encourage virus isolation attempts in cases of acute respiratory disease in rabbits, in order to gain further insight in the possible role of viruses in rabbit pneumonia.

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ARTHUR C.P., 1989. Les diverses situations de la myxomatose en France. In : Pathologie du lapin de Compagnie et des Rongeurs Domestiques, Maisons Alfort, 81-93.

CHEEKE P.R., PATTON N.M., LUKEFAHR S.D., MCNITT J.I., 1987. Rabbit production. The interstate Printers and Publishers, Danville, 213-216.

CHEVILLE N.F., 1983. Cell pathology. lowa State University Press, Ames, 462-469.

COMPANS R.W., HARTER D.H., CHOPPIN P.W., 1967. Studies on pneumonia virus of mice (PVM) in cell culture. 11. Structure and morphogenesis of the virus particle. J. Exptl Med., 126, 267-276.

GLORIOSO J.C., JONES G.W., RUSH H.G., PENTLER L.J., DARIF C.A., COWARD J.E., 1982. Adhesion of type A Pasteurella multocida to rabbit pharyngeal cells and its possible role in rabbit respiratory tract infections. Infection and Immunity, 35, 1103-1109.

JONES J.M., 1988. An update of rabbit diseases. Part 1 : respiratory disease. N. Z. Vet. J., 36, 170-177.

JOUBERT L., DUCLOS P., TUAILLON P., 1982. La myxomatose des garennes dans le sud-est. La myxomatose amyxomateuse. Rev. Med. Vet., 133, 739-753.

MACHII K., OTSUKA Y., IWAI H., UEDA K., 1989. Infection of rabbits with Sendai virus. Lab. Anim. Sci., 39, 334-337.

MARCATO P.S., ROSMINI P.R., 1986. Pathology of the rabbit and hare. Esculapio ed., Bologna, 53-59.

MARCATO P.S., BENAZZI C., VECCHI G., GALEOTTI M., DELLA SALDA L., SARLI G., LUCID! P., 1991. Clinical and pathological features of viral haemorrhagic disease of rabbits and the European brown hare syndrome. Rev. Sci. Tech. Off lnt. Epiz., 10 (2), 371-392.

MORISSE J .P., BODOLEC J .L., BOILLETOT E., MAURICE R., 1978. Infection pulmonaire expérimentale a Pasteurella multocida, influence d'un facteur irritant NH3 sur la réceptivité du lapin. Rec. Med. Vet., 154, 859-863.

MORISSE J.P., 1989. Pathologie du lapin liée aux conditions d'habitat. In : Pathologie du Lapin de Compagnie et des Rongeurs Domestiques, Maisons-Alfort, 75-80.

OKERMAN L., 1994. Diseases of Domestic Rabbits. Blackwell Scientific Publications, Oxford, 65- 70.

OKERMAN L., 1989. A comparative study of enteropathogenic Escherichia coli from rabbits. PhD thesis, Utrecht.

OKERMAN L., DEVRIESE L.A., GEVAERT D., UYTTEBROEK E., HAESEBROUK F., 1990. In vivo activity of orally administrated antibiotics and chemotherapeutics against acute septicaemic pasteurellosis in rabbits. Laboratory Animals, 24, 341-344.

OSTERHAUS A.D.M.E., TEPPEMA J.S., VAN STEENIS G., 1982. Coronavirus-like particles in laboratory rabbits with different syndromes in The Netherlands. Lab. Anim. Sci., 32, 663-665.

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Transboundary and Emerging Diseases  vol: 61  issue: 6  first page: e92  year: 2014  
doi: 10.1111/tbed.12073


 Universitat Politècnica de València


Official journal of the World Rabbit Science Association (WRSA)


e-ISSN: 1989-8886     ISSN: 1257-5011