Design and simulation of a resorbable bone fixation plate made by additive manufacturing for femoral mid-SHAFT fractures


  • J. Ivorra-Martinez Universitat Politècnica de València
  • M. A. Selles Universitat Politècnica de València
  • S. Sanchez-Caballero Universitat Politècnica de València
  • Teodomiro Boronat Universitat Politècnica de València



femur, mid-SHAFT, finite element method, resorbable, 3D printing


Finite element method has been employed to establish the feasibility of a fixation plate made of PLA by additive manufacturing for femoral shaft fractures. For this purpose, Von Mises stress and the pressure contact between bones had been analysed. The proposed design has been compared with an actual titanium fixation plate as a point of reference.


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Author Biographies

J. Ivorra-Martinez, Universitat Politècnica de València

Materials Technology Institute

M. A. Selles, Universitat Politècnica de València

Materials Technology Institute

S. Sanchez-Caballero, Universitat Politècnica de València

Institute of Design for Manufacturing

Teodomiro Boronat, Universitat Politècnica de València

Materials Technology Institute


Alizadeh-Osgouei, M., Li, Y., Wen, C. (2019). A comprehensive review of biodegradable synthetic polymerceramic composites and their manufacture for biomedical applications. Bioactive materials, 4(1), 22-36.

Arabnejad, S., Johnston, B., Tanzer, M., Pasini, D. (2017). Fully porous 3D printed titanium femoral stem toreduce stress-shielding following total hip arthroplasty. Journal of Orthopaedic Research, 35(8), 1774-1783.

Elkins, J., Marsh, J.L., Lujan, T., Peindl, R., Kellam, J., Anderson, D D., & Lack, W. (2016). Motion predicts clinical callus formation: construct-specific finite element analysis of supracondylar femoral fractures. The Journal of bone and joint surgery. American volume, 98(4), 276.

Geetha, M., Singh, A.K., Asokamani, R., Gogia, A.K. (2009). Ti based biomaterials, the ultimate choice for orthopaedic implants–a review. Progress in materials science, 54(3), 397-425.

George, D., Allena, R., Remond, Y. (2017). Mechanobiological stimuli for bone remodeling: mechanical energy, cell nutriments and mobility. Computer Methods in Biomechanics and Biomedical Engineering, 20(sup1), S91-S92,

Guastaldi, F., Martini, A., Rocha, E., Hochuli-Vieira, E., Guastaldi, A. (2019). Ti–15Mo Alloy Decreases the Stress Concentration in Mandibular Angle Fracture Internal Fixation Hardware. Journal of Maxillofacial and Oral Surgery, 19, 314-320.

Hayes, J., Richards, R. (2010). The use of titanium and stainless steel in fracture fixation. Expert review of medical devices, 7(6), 843-853.

Heimbach, B., Grassie, K., Shaw, M.T., Olson, J.R., Wei, M. (2017). Effect of hydroxyapatite concentration on highmodulus composite for biodegradable bone-fixation devices. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 105(7), 1963-1971.

Jahagirdar, R., Scammell, B.E. (2009). Principles of fracture healing and disorders of bone union. Surgery (Oxford), 27(2), 63-69.

Kanno, T., Sukegawa, S., Furuki, Y., Nariai, Y., Sekine, J. (2018). Overview of innovative advances in bioresorbable plate systems for oral and maxillofacial surgery. Japanese Dental Science Review, 54(3), 127-138.

Kim, H.J., Chang, S.H., Jung, H.J. (2012). The simulation of tissue differentiation at a fracture gap using a mechanoregulation theory dealing with deviatoric strains in the presence of a composite bone plate. Composites Part B: Engineering, 43(3), 978-987.

Klein, K.F., Hu, J., Reed, M.P., Hoff, C.N., Rupp, J.D. (2015). Development and validation of statistical models of femur geometry for use with parametric finite element models. Annals of biomedical engineering, 43(10), 2503-2514.

Li, J., Li, Z., Ye, L., Zhao, X., Coates, P., Caton-Rose, F. (2017). Structure and biocompatibility improvement mechanism of highly oriented poly (lactic acid) produced by solid die drawing. European Polymer Journal, 97, 68-76.

Li, J., Qin, L., Yang, K., Ma, Z., Wang, Y., Cheng, L., Zhao, D. (2020). Materials evolution of bone plates for internal fixation of bone fractures: A review. Journal of Materials Science & Technology, 36, 190-208.

Li, J., Yin, P., Zhang, L., Chen, H., Tang, P. (2019). Medial anatomical buttress plate in treating displaced femoral neck fracture a finite element analysis. Injury, 50(11), 1895-1900.

Liu, B., Zhang, S., Zhang, J., Xu, Z., Chen, Y., Liu, S., Yang, L. (2019). A personalized preoperative modeling system for internal fixation plates in long bone fracture surgery—A straightforward way from CT images to plate model. The International Journal of Medical Robotics and Computer Assisted Surgery, 15(5), e2029.

McClellan, R.T. (2013). The variable angle hip fracture nail relative to the Gamma 3: A finite element analysis illustrating the same stiffness and fatigue characteristics. Advances in orthopedics, 2013.

Murr, L.E. (2016). Frontiers of 3D printing/additive manufacturing: from human organs to aircraft fabrication. Journal of Materials Science & Technology, 32(10), 987-995.

Narayanan, G., Vernekar, V.N., Kuyinu, E.L., Laurencin, C.T. (2016). Poly (lactic acid)-based biomaterials for orthopaedic regenerative engineering. Advanced drug delivery reviews, 107, 247-276.

Nurettin, D., Burak, B. (2018). Feasibility of carbon-fiber-reinforced polymer fixation plates for treatment of atrophic mandibular fracture: A finite element method. Journal of Cranio-Maxillofacial Surgery, 46(12), 2182-2189.

Parthasarathy, J. (2015). 14 Additive Manufacturing of Medical Devices. Additive Manufacturing: Innovations, Advances, and Applications, 369.

Ridzwan, M., Shuib, S., Hassan, A., Shokri, A., Ibrahim, M. (2006). Optimization in implant topology to reduce stress shielding problem. Journal of Applied Sciences, 6(13), 2768-2773.

Sariali, E., Mouttet, A., Pasquier, G., Durante, E. (2009). Three-dimensional hip anatomy in osteoarthritis: analysis of the femoral offset. The Journal of arthroplasty, 24(6), 990-997.

Singh, D., Singh, R., Boparai, K.S. (2018). Development and surface improvement of FDM pattern based investment casting of biomedical implants: A state of art review. Journal of Manufacturing Processes, 31, 80-95.

Spiridon, I., Tanase, C.E. (2018). Design, characterization and preliminary biological evaluation of new lignin-PLA biocomposites. International journal of biological macromolecules, 114, 855-863.

Tang, G., Liu, S.L., Wang, D.M., Wei, G.F., Wang, C.T. (2013). Finite element analysis in femoral fixation with TA3 titanium compressioll plate. In Advanced Materials Research, 647, 16-19. Trans Tech Publications Ltd.

Tymrak, B., Kreiger, M., Pearce, J.M. (2014). Mechanical properties of components fabricated with open-source 3-D printers under realistic environmental conditions. Materials & Design, 58, 242-246.

Wang, A.Y., Peng, J., Sun, M.X., Sui, X., Wang, X., Tian, Y., Lu, S.B. (2006). Biomechanical comparison of different structural bone grafting in femoral heads’ defects of weight-bearing region. Journal of Medical Biomechanics, 4.

Wang, J., Ma, J.X., Lu, B., Bai, H.H., Wang, Y., Ma, X.L. (2020). Comparative finite element analysis of three implants fixing stable and unstable subtrochanteric femoral fractures: Proximal Femoral Nail Antirotation (PFNA), Proximal Femoral Locking Plate (PFLP), and Reverse Less Invasive Stabilization System (LISS). Orthopaedics & Traumatology: Surgery & Research, 106(1), 95-101.

Wang, X., Xu, S., Zhou, S., Xu, W., Leary, M., Choong, P., Xie, Y.M. (2016). Topological design and additive manufacturing of porous metals for bone scaffolds and orthopaedic implants: A review. Biomaterials, 83, 127-141.

Wu, C., Zheng, K., Fang, J., Steven, G.P., Li, Q. (2020). Time-dependent topology optimization of bone plates considering bone remodeling. Computer Methods in Applied Mechanics and Engineering, 359, 112702.

Wu, K.J., Li, S.H., Yeh, K.T., Chen, H., Lee, R.P., Yu, T.C., Wang, J.H. (2019). The risk factors of nonunion after intramedullary nailing fixation of femur shaft fracture in middle age patients. Medicine, 98(29).

Wu, X., Wang, Z., Li, H., Li, Y., Wang, H., Tian, W. (2019). Biomechanical evaluation of osteoporotic fracture: Metal fixation versus absorbable fixation in Sawbones models. Injury, 50(7), 1272-1276.

Zhao, X., Niinomi, M., Nakai, M., Hieda, J., Ishimoto, T., Nakano, T. (2012). Optimization of Cr content of metastable β-type Ti–Cr alloys with changeable Young’s modulus for spinal fixation applications. Acta biomaterialia, 8(6), 2392-2400.